Enhancement of immune responses to an HBV DNA vaccine by electroporation.

نویسندگان

  • A Luxembourg
  • D Hannaman
  • B Ellefsen
  • G Nakamura
  • R Bernard
چکیده

These studies document the ability of electroporation (EP)-based DNA vaccination to induce multi-specific CTL responses to hepatitis B virus (HBV) DNA vaccination in normal mice and marked immune responses to multivalent HBV DNA immunization in larger animal species. These results suggest that electroporation-mediated HBV DNA vaccination is worth pursuing as a treatment for chronic HBV infection.

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عنوان ژورنال:
  • Vaccine

دوره 24 21  شماره 

صفحات  -

تاریخ انتشار 2006